chapter 17: Genetics
Replication of DNA
Mutations
Monohybrid Crosses
Dihybrid Crosses
Concepts
Genetics - The science of inheritance
Allele - nucleotide sequence for a specific gene. - arises from mutation
genotype - the types of alleles that a single individual has
Genotype - the physical expression of the alleles a person has.
DNA is replicated during the S phase of the cell cycle, before undergoing mitosis or meiosis.
step 1: chromatin breaks apart
- one strand of the double helix is cut, the 2 strands separate from each other and form a small bubble called a replicon.
- once the helix is open, free ribonucleotides diffuse to regions of single stranded DNA and pair with the base along both strands. they then polymerize and form primer RNA
semiconservative replication - each strand of DNA acts as the template for making the complementary strand
- replication fork - when the DNA uncoils and separates and looks like a fork
- finally, each replication fork runs into one of the adjacent replicons; all new DNA are then ligated into new , complete molecules
mutation - any change in DNA
point mutation - when a single base is converted to another base by any methods.
types of mutation
Deletion - when a piece of DNA is lost
insertion - the addition of extra DNA
inversion - a piece of DNA becomes tangled and breaks, when repaired it is put in backwards
Mutagen - something that causes mutations
somatic mutation - happen in cells that that never lead to sex cells
cross- sexual reproduction between 2 individuals
parental generation- parents
homozygous - 2 identical alleles for a certain gene
first filial generation (F1)- the offspring
F2 - if F1 interbreeds
heterozygous - 2 different alleles for a gene
incomplete dominance - when no parental trait dominates the other
selfing - when a plant's own pollen is used to fertilize its own eggs
Punnett Square - boxes used to determine the genetic outcomes of a cross
dihybrid cross - when 2 genes are analyzed simultaneously instead of just 1
independent assortment - when the alleles of one gene moves independently of the alleles of the other gene
crossing over - the exchange of genes in meiosis