chapter 17: Genetics

Replication of DNA

Mutations

Monohybrid Crosses

Dihybrid Crosses

Concepts

Genetics - The science of inheritance

Allele - nucleotide sequence for a specific gene. - arises from mutation

genotype - the types of alleles that a single individual has

Genotype - the physical expression of the alleles a person has.

DNA is replicated during the S phase of the cell cycle, before undergoing mitosis or meiosis.

step 1: chromatin breaks apart

  1. one strand of the double helix is cut, the 2 strands separate from each other and form a small bubble called a replicon.
  1. once the helix is open, free ribonucleotides diffuse to regions of single stranded DNA and pair with the base along both strands. they then polymerize and form primer RNA

semiconservative replication - each strand of DNA acts as the template for making the complementary strand

  1. replication fork - when the DNA uncoils and separates and looks like a fork
  1. finally, each replication fork runs into one of the adjacent replicons; all new DNA are then ligated into new , complete molecules

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mutation - any change in DNA

point mutation - when a single base is converted to another base by any methods.

types of mutation

Deletion - when a piece of DNA is lost

insertion - the addition of extra DNA

inversion - a piece of DNA becomes tangled and breaks, when repaired it is put in backwards

Mutagen - something that causes mutations

somatic mutation - happen in cells that that never lead to sex cells

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cross- sexual reproduction between 2 individuals

parental generation- parents

homozygous - 2 identical alleles for a certain gene

first filial generation (F1)- the offspring

F2 - if F1 interbreeds

heterozygous - 2 different alleles for a gene

incomplete dominance - when no parental trait dominates the other

selfing - when a plant's own pollen is used to fertilize its own eggs

Punnett Square - boxes used to determine the genetic outcomes of a cross

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dihybrid cross - when 2 genes are analyzed simultaneously instead of just 1

independent assortment - when the alleles of one gene moves independently of the alleles of the other gene

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crossing over - the exchange of genes in meiosis