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Q20: Explain the role and mechanism of vesicular sorting and transports -…
Q20: Explain the role and mechanism of vesicular sorting and transports
Proteins for vesicular target and fusion
Scaffolds
v-SNARE
t-SNARE
Rab effector
ER --> Golgi
COPII
Golgi
--> Golgi
Vesicle transport model between cisternae
--> Lysosome
Clathrin
--> ER
COPI
--> Plasma membrane
Constitutive secretory pathway
Regulated secretory pathway
Plasma membrane <--> Endosomes
Clathrin
Pathways of deliver to Lysosomes
Endocytosis
Macropinocytosis
Phagocytosis
Autophagy
Macroautophagy
Chaperone-mediated autohagy
Microautophagy
Exocytosis
Microvesicles
Multivesicular bodies (MVB)
Exosomes
Endosomes form direclty synaptic vesicles