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MEMBRANE BOUND RECEPTORS - Coggle Diagram
MEMBRANE BOUND RECEPTORS
INTERNAL RECEPTORS
hydrophobic ligands
modify mRNA synthesis
ligand-receptor complex
travel to the nucleus
steroid hormones
CELL-SURFACE RECEPTORS
transmembrane
ligand-receptor complex
signal transduction
specificity
types
ion-channel receptor
opening of a channel
movement of ions
membrane-spanning region
change in shape of the receptor due to ligand binding
GPCR
G-protein
trimeric protein
alpha subunit dissociates when bound to GTP
examples of second messengers: cAMP, DAG, IP3, PLC beta
second messenger cascade
activating and inhibiting action
enzyme-linked receptor
catalytic site in the cytoplasimc region
dimerization
types
RTK
RSTK