Chapter 17: Genetics

Gregor Mendel Mendel

Died: 6 January 1884 (age of 61) Brunn, Moravia, Austria-Hungary (now Brno, Czech Republic)

Born: Johann Mendel 20 July 1822 Heinzendorf bei Odrau, Silesia, Austrian Empire (now Czech Republic)

Was a Christian and ordained 25 December 1846

Meteorologist, Mathematician, Biologist, Augustinian friar, and abbot of Saint Thomas' Abbey in Brno, Margraviate of Moravia

Was born in a German-speaking family

key components

chromosome

DNA

RNA

genome

heredity

mutation

nucloetide

variation

History and Topics

Evolution (molecular)

Population genetics

Mendelian inheritance

Quantitatie genetics

Molecular genetics

began working on pea plants, published in 1866, established the theory of Mendelian inheritance.

Mendel's Laws of Heredity

1) The Law of Segregation

2) The Law of Independent Assortment

3) The Law of Dominance

What 7 traits Mendel researched

1) Pea Shape (round or wrinkled)

2) Pea color (green or yellow)

3) Pod shape (constricted or inflated)

4) Pod color (green or yellow)

5) Flower color (purple or white)

6) Plant size (tall or dwarf)

7) Position of flowers (axial or terminal)

Using pea plants allowed him to understand the means by which traits are inherited between parent an offspring.

Pea plants were easy to grow, could be bred rapidly, and had several observable characteristics, like petal color and pea color.

definitions

replicon: one strand of the DNA double helix is cut, and the two strands separate from each other in a short region, forming a small "bubble"

primer RNA: during DNA replication, a short piece of RNA that is synthesized against open DNA and from which DNA polymerase can begin building a new molecule of DNA.

DNA polymerase: enzymes that synthesize the formation of new molecules of DNA, using a strand of an existing DNA double helix as a guide.

semiconservative replication: refers to the fact that during DNA replication, one new molecule such that in every new chromosome, half the DNA is conserved from the pre-existing chromosome.

alleles: versions of a gene that differ from each other in their nucleotide sequences

genotype: the set of alleles present in an organism's genome.

phenotype: the physical, observable characteristics of an organism.

causes of mutation

mutagen

certain chemicals, ultraviolet light, x-rays, and radiation from radioactive substances

DNA

T=A

G=C

C=G

A=T