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Antagonists/ Antidotes - Coggle Diagram
Antagonists/ Antidotes
Block MU and kappa receptors
naloxone
Acute overdose
naltrexone
Reduce euphoria in alcohol dependency
Decrease cravings
methylnaltrexone
Relieve opioid caused constipation
Indications
Reverse the effects of agonist
Treats respiratory depression
Relieve opioid caused constipation
Adverse Effects
Tachycardia & Tachypnea
Abstinence Syndrome
Cramping, hypertension, vomiting, fever, and anxiety
abrupt onset of pain
Contraindications
Opioid dependence patients
Liver Failure
Nursing Actions
Shorter half-life than opioid
Monitor respirations for 2 hrs after
Give Naloxone IV