Group 2 - Immunity
B cells by HF
T Cells by RI
AH Immunopathology
Major Divisions
MM
Cell-mediated immunity
Humoral immunity
The production of antibodies (b-cells as primary cells); responsible for protection against pathogenic microorganisms
Lymphocytes (T-cells) working alone or assisted by macrophages regulating both major divisions.
:
click to edit
The study of diseases caused by the malfunctioning of the immune system
.
4 types of hypersensitivity; type 1 (anaphylactic) Those who have asthma are said to be in this category, hay fever and anaphylactic shock which is life threatening. Type 2 (cytotoxic) incompatible blood transfusions, Type 3 (immune complex) results in acute inflammatory response, Type 4 (cell mediated) takes 2-3 days to develop, rejection of tissue grafts, transplanted organs, dental restorations or jewelry containing nickel
The immunopathologic conditions include hypersensitivity(allergies), autoimmune disease, and immunodeficiency
Types of Immunity BW
Passive
Active
Mother to Child
Blood transfusion of antibodies
Autoimmune disease where the immune system treat the body's cells as antigens
Infection via exposure to an antigen
Immunization
Immunodeficiency involves a compromised or absent immune system. Can be congenital or acquired.
T Cell: This lymphocyte matures in the thymus. A T-cell responsibility is mainly to initiate cell-mediated immunity as well as modulating humoral immunity.
Cytokines: These are proteins produced by various cell types. The purpose of Cytokines is intercellular communication or signaling. Cytokines are involved as biochemical
Natural Killer Cell: This lymphocyte is part of the initial innate immune response. NK cells is able to directly destroy cells recognized as foreign.
B-cell: A type of lymphocyte that develops in lymphoid tissue that can develop into a plasma cell that produces an antibody, the main initiator for humoral immunity.
Macrophages: The second type of white blood cell to arrive at the site of injury. It was originally a monocyte and it participates in phagocytosis during inflammation. It continues to be active during the immune response.
Dendritic cells: Its main focus is to process antigenic material and present it on its surface to other cells of the immune system