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Pueraria montana - Coggle Diagram
Pueraria montana
Brown University Digest of Addiction Theory and Application
Beverages
Not actually used in beverage
used as reducing agent for alcohol consumption
extract of herbal root
contains 3 isoflavones
puerarin
daidzin
daidzein
volunteers
consumed 25 alcoholic beverages/week
exclusions
alcohol dependent
recently detoxified
seeking treatment
family history of alcoholism
pregnant women
on prescription drugs/OTC meds
asked to refrain from aspirin containing products
BMI b/w 19 and 24kg/m^2
experiment
double-blind
no side effect in either group
treatments
placebo
kudzu extract
2 500mg capsules
3 times daily
7 days
given opportunity to drink >/= 6 beers
kudzu subjects
urine + blood analysis
100% compliance
did not alter any varible
liver function
hematology
blood chemistry
1 week of treatment
reduction in number of beers drank
1 subject opened 5th beer
no one drank all 6
when on placebo
2 drank all 6
weaknesses
small sample size
omission of control groups
uses on pregnant women, adolescents, vulnerable populations
yet to be seen