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Lesson 12 - Coggle Diagram
Lesson 12
Immunoevasion
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Inactivate Immune cells
Treg cells and cancer cells release immunosuppressive cytokines to inhibit activation of naïve T cells
Tregs express CTLA-4 on their surface, which downregulate B7 (CD80) expression by antigen presenting cells (APC), depriving co-stimulatory signal to responder T cells.
Immunotherapy
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Antibody-Drug Conjugate
antibodies conjugated with anti-cancer drugs bind to cancer cell, delivering a toxic that can kill them
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