The kidney's role in homeostasis

Regulates blood pressure

PH balance

Renin released by glomerulus

Kidney excretes hydrogen lons and reabsorbs bicarbonate ions to maitain blood PH

Electrolytes balance

Regulates ions by reabsorption & secretion

Fluid volume balance

Releases ADH receptors

Rrgulates and balance the amount of water in blood

Increases Red blood cell production

Potassium,
sodium

Calcium

Phosphate

Aldostenme regulates the absorptio and secretion of sodium and potassium

Calcium reabsorption occurs depending on the level of circulationg PTH

Reabsorbed in the proximal tubule when plasma level is low; excreted in the urine when it is high in plasma

Magnesium

Incresed PTH results in increased tubular reabsorption of magnesium in kidney

Removal of waste products

Excess ions

Matabolic waste

Drug metabolites

Hormone metabolites

sodium, potassium, calcium, manisium, chlorlde, bicarbonate, phosphate and ammonium

urea, creatinine. uric acid, nitrogenous waste

most drugs are detoxifield in liver and then excreted through the kidney

eg. HCG-excretion through the kidney

produce angiotension I which then converted to angiotension II

Vasoconstriction - increases Bp

Kidney produces
Erythopoitin

Erythopoietion stimulates RBC. production when the body is hypoxia

Produces Aldosterone

Regulates sodium reabsorption and in turn water reabsorption