The kidney's role in homeostasis
Regulates blood pressure
PH balance
Renin released by glomerulus
Kidney excretes hydrogen lons and reabsorbs bicarbonate ions to maitain blood PH
Electrolytes balance
Regulates ions by reabsorption & secretion
Fluid volume balance
Releases ADH receptors
Rrgulates and balance the amount of water in blood
Increases Red blood cell production
Potassium,
sodium
Calcium
Phosphate
Aldostenme regulates the absorptio and secretion of sodium and potassium
Calcium reabsorption occurs depending on the level of circulationg PTH
Reabsorbed in the proximal tubule when plasma level is low; excreted in the urine when it is high in plasma
Magnesium
Incresed PTH results in increased tubular reabsorption of magnesium in kidney
Removal of waste products
Excess ions
Matabolic waste
Drug metabolites
Hormone metabolites
sodium, potassium, calcium, manisium, chlorlde, bicarbonate, phosphate and ammonium
urea, creatinine. uric acid, nitrogenous waste
most drugs are detoxifield in liver and then excreted through the kidney
eg. HCG-excretion through the kidney
produce angiotension I which then converted to angiotension II
Vasoconstriction - increases Bp
Kidney produces
Erythopoitin
Erythopoietion stimulates RBC. production when the body is hypoxia
Produces Aldosterone
Regulates sodium reabsorption and in turn water reabsorption