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Epithelium / Connective Tissue / Cartilage / Bone / Joint - Coggle Diagram
Epithelium / Connective Tissue / Cartilage / Bone / Joint
Connective Tissue
Tissue Fibers
Collagen Fibers
Stretching skin too far (Pregnancy) can lead to damaged collagen fibers causing stretch marks
Reticular Fibers
Elastic Fibers
Made of:
Collagen Fibers (Noodles)
Ground Substance (Broth)
Cells (chicken)
Types of Connective Tissue
Loose CT
Dence Irregular CT
Dense Regular CT
Function:
Make up:
Elastic Connective Tissue
Collagen
Made of
Alpha units wrapped tight around each other, forming a fibril
Then, many layers of fibrils form collagen
Types of Collagen
Type 1 (90% of body)
Dermis, tendons, ligaments, fibrocartilage, bone, joint capsules
Function: Resisting tension & Stretching forces
Type 2
Hyaline cartilage, elastic cartilage, & fibrocartilage
Function: Will resist compression forces
Type 3
Reticular fibers
Organs, blood vessels, endoneurium of nerves
Function: Wound closure
Type 4
Basement membrane of epithelial
Axons
Type 5
Basal Lamina of smooth & skeletal muscle
Schwann and glial cells
Cells that produce Collagen
Fibroblast
Primary cells of Connective tissue
Chondroblast
Produce cartilage
Osteoblast
Produce Bone
Skeletal Muscle Cells
Produce collagen in skeletal muscle
Smooth muscle cells
Produce Collagen in smooth muscle (blood vessels)
Collagen is part of Connective Tissue
Clinical Points
Sprain
Microfalure of ligament
Strain
Microfalure of tendon
Tendonitis
Inflammatory response of a tendon
Tenosynovitis
Synovial fluid around the joint becoming inflamed
Due to stress, damage, overload
Tendon/Ligament Strengtheing
Stepwise progression of stress & load to strengthen the tissues
Loading/planes/range of motion
Arthritis
Osteoarthritis
Articular hyaline cartilage and subchondral bone becoming impacted over time from load/stress and is damaged
Rhomitoidarthritis
A systematic inflammatory disease that attacks the synovial fluid around the joint. Progressing into malformation of joint structure
Cartilage
Hyaline
Made of type 2 collagen
Ex. Auricle of ear, epiglottis, wall of external auditory canal
Elastic
Fibrocartilage
Made of type 1 and type 2 collagen
Ex. TMJ, sternoclavicular joint, intervertebral disc
Damage & Repair
Cartilage is:
Avascular
Aneural
Can be damaged by:
Overloading
Underloading
Disease (Osteoarthritis)
Repair LIMITED
Blood from subchondral bone forms fibrous scar
Scar matures and forms fibrocartilage "scar tissue"
Bone
Composition
Osteocytes
Bone Matrix
Cells of bones
Osteocytes
SImply Mature osteoblast
Osteoblast
"Immature Osteocytes"
Secrete Collagen and osteoid
Osteoclast
Remove bone & Osteoid for growth and remodeling
Osteogenic Cells
Develop into Osteoblast
When Osteoblast become trapped within the calcified mix of bone, they become "Osteocytes"
Structure
Hyland cartilage on end of bones
Periosteum
Outer layer of bone, made of Dense Irregular CT
Causes bone width growth
Endosteum
Lines internal of bone
Has Haversian Canal
Function: house nerver fibers and few capillaries
Shaft
"Dyaphysis"
Has the "Primary Ossification Center"
Ends of bones
"Epiphyseal"
Rounded end of a long bone
Has the "Secondary Ossification Center"
Epiphysial plate "Growth Plate"
During growth only, is between the diaphysis & Epiphysis
When growth is done, diaphysis & epiphysis fuse, forming the epiphysial line
Healing Process
Begins with hematoma "Blood Clot"
Capillaries form granulated tissue
Granulated tissue become dense CT
Hyaline & fibrocartilage develop
Begins remodeling phase
Microphages remove dead tissue
Osteoclast remove bone fragments
Joints
Diarthrosis
Moveable joint
Synovial Joint, has synovial fluid
Joint types:
Plane / Arthrodial
Intercarpal or AC Joint
Hinge / ginglymus
Interphalangeal or humerousulnar
Pivot / trochoid
Proximal Radioulnar
Condyloid / ellipsoid
Radiocarpal / MCP
Saddle / Sellar
Sternoclavicular
Ball & Socket / enarthrodial
Glenohumeral / acetabulofemoral
Features:
Capsule
Within joint capsule:
Stratum Fibrosum: Rich in joint receptors, poorly vascularized
Stratum Synovium: Highly vascularized, poorly innervated
Cavity
Synovial membrane
synovial fluid
hyaline cartilage
Synarthrosis
Fibrosis
Syndesmosis Joint
Joining of bones by ligamentous tissue
Example: Interosseous membrane of radius/ulna
Suture Joint
Found in cranial bones
Cartilaginous
Synchondrosis Joint
Cartilaginous joint, with HYALINE CARTILAGE at the epihysis (end) of long bones
Example: Costal cartilage of ribs to sternum
Symphysis Joint
2 bones joined by disc or fibrocartilage. Allows some movement
Example: Pubic symphysis, Intervertebral Disc
Epithelium
Skin
Epidermis
4 to 5 layers of stratified squamous eipthelum
Avascular
Stratum Basale "deepest layer of epidermis"
Contains:
Keratinocytes
Melanocytes
Merkel cells
Dermis
2 layers under Epidermis:
Reticular Layer
Dense Fibrous CT
Papillary Layer
Loose CT
Contains blood vessels, NERVE ENDINGS, sweat glands, sebaceous glands, sensory receptors
Subcutaneous layer
Contains loosely arranged collagen & elastic fibers
Fat cells, nerves, large blood vessels
Burns
1st degree
Localized, Painful. Like a bad sunburn
2nd Degree
Superficial dermal: Epidermis & Upper dermis
Blister formation, Very Painful
3rd degree
Epidermis, dermis, subcutaneous layer
Prone to infection, Painless
4th degree
Epidermis, dermis, subcut, muscle/bone
Black, Loss of fluid, Prone to infection
Ulcers "Bed Sores"
Stage 1
Partial Epidermis, Slight edema, Painful
Stage 2
Partial Epidermis & Dermis
Shallow ulcer, Painful
Stage 3
Full Thickness Depth, Muscle exposed
Deep draining ulcer, foul oder, painless
Stage 4
Full thickness, includes muscle
Bone Exposed, large wound, drainage, painless
Forces/Loads
Axial/Compression
Landing from a jump. Compression of the bone/joint (force is through the axis of bone)
Shear (Torsion)