Type 1 (intermediate) Ch.18 lecture 2
S/S
mild and localized
site of infection depends on portal of entry
Inhaled allergens
hay fever
runny nose, sneezing, itching
asthma
wheezing, coughing, excessive production of thick, sticky mucus
Inflammation of skin
hives, urticaria
latex, wool, venom of wasps, bees, deer flies, fleas, etc.
Anaphylaxis
S/S
rapid suffocation
Bronchial smooth muscle contracts then increase of fluid from blood vessels causes swelling of larynx and other tissues
bee stings, peanuts, vaccines containing egg proteins, antibiotics like PCN, iodine dyes, local anesthetic blood products and morphine
Dx
immunCAP, specific IgE blood test, CAP REST, pharmacia CAP
Prevention
filter air, avoid rural areas during pollen season, encasing bedding, vaccuming and avoiding furniture that can trap dust
Tx
Antihistamine
neutralized histamine
Asthma
glucocorticoid and bronchodilator
Epinephrine
neutralizes chemicals in anaphylaxis