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Hypersensitivity Ch.18 lecture 1 - Coggle Diagram
Hypersensitivity Ch.18 lecture 1
Examples
wearing wool, smelling perfume or dust furniture.
S/S
itching, wheezing, runny nose, watery eyes
4 types
type 1 (intermediate)
type 2 (cytotoxic)
type 3 (immune complex-mediated)
type 4 (delayed or cell-mediated)
Type 1 (immediate)
localized or systemic reaction results from release of inflammatory molecules in response to antigen
called allergies, antigens that stimulate it called allergens
step 1
Sensitized upon initial exposure to an allergen
Step 2
roles of degranulating cells in an allergic reaction
leukotrienes
cause slow, prolonged muscle contraction, inflammation, and leaking
Prostglandins
Contract smooth muscle while others will relax it
Basophils
bind with IgE and degranulate the same as mast cells
Eosinophils
in bloodstream can degranulate release of leukotrines and increase severity of a hypersensitivity response.