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prazosin (Minipres) - Coggle Diagram
prazosin (Minipres)
Mechanism of Action
- competes with NE at alpha receptor to block binding
Administration Alerts
- short half life ( must be given 2-3 x/d)
- begin with low dose to avoid hypotension
Adverse Effects
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- Unconsciousness 30 min post 1st dose
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- inhibition of ejaculation
Treatment Overdose
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- Vasopressors (dopamine, dobutamine)
Drug-Drug Interactions
- additional anti-hypertensives = extremely low BP
- added diuretics = lowering BP
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Contraindications
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- allergies to drug or components of drug
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