atropine (Atropen)
Mechanism of Action
Anti-Muscarinic
- Increase HR
- bronchodilates
- decrease gastric motility
- Mydriasis
Administration Alerts
USES
- antidote for anticholinesterase poisoning
- Monitor BP, Pulse, Respirations
- Monitor 1 hour before & after administration
Why??
PNS drugs dilate bronchioles, increase HR, & increase BP
Adverse Effects
- Dry mouth
- Constipation
- Urinary retention
- increase HR
- CNS excitement = delirium if worsens
CAUTION: Patients with Bladder function issues, or BP issues should NOT take drug
Treatment Overdose
physostigmine (Antilirium)
Drug-Drug Interaction
Anything that accentuates PNS lytic response (procainamide, TCA)
Herbal Interactions
Contraindications
saw palmettto increases effect of atropine
- Glaucoma Patients
- Obstructive patients (GI & Bladder)
- Benign prostatic hyperplasia
- Myasthenia gravis