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Pharmacology of Antibacterial Drugs I - Coggle Diagram
Pharmacology of Antibacterial Drugs I
Two reasons for antibiotic therapy
treatment of active infection
treatment for 7-19 days
gives time for immune system to do its thing
Prophylaxis
single dose to cut things short (eg. endocarditis)
Targets of antibiotics
Bacteria
cell walls/membranes
protein synthesis
DNA/RNA synthesis
Fungi
cell wall/membrane
steroid synthesis
Viruses
DNA/RNA synthesis
Absorption/processing/assembly
Parasites
Unique location in GI
Toxicities and Complications
Hypersensitivity
Superinfection
Most common in extended or broad spectrum antibacterial drugs
Not a problem in antifungal, antiviral, or antiparasitic drugs
C diff
Candida albicans
Organ-specific
if underlying condition
Drug Interactions