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Biological and Genetic affects on Population Health - Coggle Diagram
Biological and Genetic affects on Population Health
Risk Assessment
Investigate genetic profiles as components
Genetics may provide a window into clinical heterogeneity
May be useful in understanding differences:
persistence
comorbidity
response to treatment
rate of progression
timing of onset
Understanding of Environmental Causation
Collaborate with geneticists on gene–environment interaction research
Genes and environments is critical to public health translation of genome science
Guiding principal of personalized medicine
Hold a key to understanding the etiology of conditions like asthma and obesity
Targeted Intervention
Conduct life-course longitudinal studies to understand when genetic risks manifest in development and whether intervention during sensitive periods can have lasting effects
3 questions:
With whom should we intervene?
Identify individuals who will develop disease or respond to treatment
When should we intervene?
Identify sensitive or critical periods in pathogenesis when intervention could be most effective
How should we intervene?
Inform the selection of intervention targets
Biological Processes
Determined by: determined by social, cultural, and environmental factors
Metabolism and homeostasis
Our lifestyles impact biological processes
