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Diarrheagenic E coli - Coggle Diagram

- - - - hemorrhagic colitis
      - HUS
  - - - dysentery
      - bowel ulceration
  - - - heat labile
      - heat stable
  - - - travelers diarrhea
      - persistent acute diarrhea
- - - - action
        
        fragment A
        
        Fragment B
        
        binds to GB3 receptor
        
        entry of A fragment
        
        60s ribosomal subunit inhibited
      - bacteriophage coded
      - EHEC
    - - ETEC
      - plasmid coded
      - MOA
        
        bind to guanylate cyclase C
        
        ⬆️cGMP
        
        ⬆️fluid accumulation in gut lumen
        
        diarrhea
    - - produced by ETEC
      - plasmid coded
      - action
        
        A
        
        B
        
        binds to GM1
        
        A fragment entry
        
        Gprotein adenylation
        
        camp accumulation
        
        1 more item...
      - similar to Cholera toxin