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Anemias - Coggle Diagram

- - - - Alpha-thalassemia
      - Beta-thalassemia
- - - - Membrane defects
        
        Hereditary spherocytosis
        
        MCV is low, but mean corpuscular hemoglobin concentration (MCHC) is high due to RBC dehydration and membrane loss
        
        basically, due to the decreased overall volume of the RBCs (low MCV) while hemoglobin concentration remains the same, MCHC increases (hemoglobin is concentrated in less RBCs)
        
        Paroxysmal nocturnal hemoglobinuria (PNH)
      - Enzyme deficiencies
        
        G6PD deficiency
        
        Pyruvate kinase deficiency
      - Hemoglobinopathies
        
        Sickle cell anemia
        
        HbC disease
    - - Autoimmune hemolytic anemia (AIHA)
        
        Warm AIHA
        
        Cold AIHA
      - Microangiopathic hemolytic anemia
      - Macroangiopathic hemolytic anemia
      - Hemolytic anemia due to infection
- - - - Folate deficiency
      - Vitamin B12 deficiency (pernicious anemia/Addison's anemia)
      - Orotic aciduria
    - - Fanconi anemia