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CANINE DISTEMPER VIRUS - Coggle Diagram
CANINE DISTEMPER VIRUS
Shedding of virus in body secretions of acutely infected animals
Transmitted by direct contact or aerosol infection
Incubation period (1-2 weeks)
Replicates in the lymphatic tissue
Viraemia
Infects upper respiratory tract
Pyrexic
Serous nasal discharge, mucopurulent ocular discharge
Infects integumentary system
Migrate below epithelium
of visceral organ and skin
Invades the keratocytes of the nasal planum and foot pads
Hyperkeratosis of the nasal and foot pad
Infects central nervous system
Virus replication
Demyelination
Encephalomyelitis
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Rapid virus replication and destroy actively dividing
cells
Lymphocytolysis
Lymphopenia
Immunosuppression
Susceptible to secondary bacterial infection