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DNA Replication - Coggle Diagram
DNA Replication
DNA Polymerase
Only works 5' to 3'
12 are found in humans, and 5 in
E.coli
cannot begin synthesis on a bare
template strand ( requires primer)
Removes RNA primers and replacing it
with DNA
Leading strand
Legging strand
DNA Proteins
DNA topoisomerase
Single- strand binding proteins
DNA helicase
Models
Conservative
1 double helix with parental strands
2 new daughter strands
Dispersive
Segments of new DNA are interspersed
with the partenal DNA
Semiconservative
Two new double helices with same base
sequence as original
1 newly- made
daughter strand
1 Original parental strand
Molecular mechanism
Single origin
Bacteria
Multiple origins
Eukaryotes
Origin of replication forms two forks
(DNA begin replication)
Accuracy of DNA replication
Active site of DNA polymerase
DNA polymerase can proofread to remove
mismatched pairs
Hydrogen bonding between A-T, and G-C