Please enable JavaScript.
Coggle requires JavaScript to display documents.
Membrane structure, synthesis, and transport - Coggle Diagram
Membrane structure, synthesis, and transport
-
Fluid mosaic model
- Membrane is a mosaic of lipid, protein, carbohydrates.
- lipids and proteins can move
-
Fluidity
- Membranes are semifluid
lipids movement:
- Laterally movement
- Rotate
- Flip-flop (needs ATP)
Factors affecting fluidity:
- Fatty acyl tails length
- Double bonds
- Cholesterol
Some integral membrane proteins can't move:
- bounding to components of the cytoskeleton
- attaching to molecules that are outside the cell
Synthesis of :
Lipids:
- at cytosolic leaflet of the smooth ER.
Transfer lipids to other membranes:
- diffuse laterally.
- Via vesicles.
- Lipid exchange proteins.
Transmembrane proteins:
- Most are directed to the ER membrane first .
- from ER to other membranes via vesicles.
Carbohydrates:
- Glycosylation: attaching a carbohydrate to a protein or lipid
- important in cell surface recognition.
- N linked glycosylation
- O linked glycosylation
-
Phospholipid bilayer barrier: Hydrophobic interior
- Diffusion depends on solute chemistry.
-