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SLE, Muhammad Zubair, 2108260216 - Coggle Diagram
SLE
Risk factors
Gender
Age
Genetic
Smoking
Vitamin D deficiency
Komplikasi
Urologi : lupus nefritis, gagal ginjal
Neurologi : gangguan memori, gangguan bahasa, gangguan kognitif
Kardiovaskuler : anemia, vaskulitis, perikarditis,
Respirasi : pleuritis, efusi pleura, pneumonia
Muskuloskeletal : osteoporosis, fraktur
DD
Rheumatoid Arthritis
Non-Hodgkins Lymphoma
Sjorgen syndrome
CMD
Physical Examinations
Clinical Examinations: ANA, anti-dsDNA
Anamnesis
Definition and etiology
Autoimmune disease causing chronic inflammation.This disease occurs in the body due to the immune systemThe body mistakenly attacks healthy tissue.
interactions between susceptibility genes (inclalleles HLA-DRB1,IRF5, STAT4, HLA-A1, DR3, and B8),hormonal influences, and environmental factors. Third interactionThese factors will cause an immune responseabnormal
Education & Prognosis
Explanation of sle, causes, and complications. Sufficient physical activity, ways to reduce or prevent relapse among other things. protect the skin from exposure to sunlight by using sunscreen, umbrella or top
The survival rate in SLE patients is 90% to 95% after 2 years, 82% to 90% after 5 years, 71% to 80% after 10 years, and 63% to 75% after 20 year.
Treatments
Avoid sunlight or cover with clothing to Prevent problems caused by photosensitive. Reducing body weight is also recommended in obese patients and overweight, especially when there is a problem with joint.
NSAIDs: aspirin, ibuprofen, naproxen, and sulindac
Pathophysiology & pathogenesis
Autoimmune disease concept
Autoimmune disease happens when the body's natural defense system can't tell the difference between your own cells and foreign cells, causing the body to mistakenly attack normal cells. There are more than 80 types of autoimmune diseases that affect a wide range of body parts.
Muhammad Zubair
2108260216
