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Haemophilia - Coggle Diagram
Haemophilia
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Diagnostic Algorithm
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Supporting examination
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Hemostasis test
Bleeding time, aPTT, PT, Clotting factor test, fibrinogen test.
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Treatment
Pharmacology
Desmopressin, Cryoprecipitate, IV clotting factors, Fresh Frozen Plasma
Non- Pharmacology
Compression, bandaging joints/muscles for
stabilization and reduce bleeding.
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Patomechanism
A deficiency of any of the essential clotting factors will result in difficulty forming a fibrin clot, and excessive bleeding can occur. Bleeding disorders fall into two main categories: inherited and acquired. Inherited bleeding disorders have a genetic predisposition and involve a deficiency of coagulation factors. Acquired bleeding disorders can be caused by conditions that an individual may develop at any point during their lifetime. These can be broader in range and dependent on comorbid conditions.
Etiology of Hemophilia
Hemophilia is caused by a mutation or change, in one of the genes, that provides instructions for making the clotting factor proteins needed to form a blood clot.
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