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cholinergic drugs - Coggle Diagram

- - - - HEART
        
        Gi coupled
        
        decrease the AC
        
        decrease cAMP
    - - eye,glands
        
        Gq
        
        increase phospholipase C
        
        increase IP3,DAG and Ca+2
  - - - methacoline
      - carbachol mainly eye
        
        produce miosis in eye
        
        treatment for open angle or narrow angle glucoma
      - bethanachol mainly GI,GU
        
        side effects
        
        hypotension and increases GI motility ,bronchoconstriction
        
        treat by atropine
      - ACh mainly eyes
        
        poor solubility and short duration of action
        
        constriction of eyes
        
        decrease HR and BP
        
        stimulate GIT and urinary system
    - - nicotine
      - pilocarpine
        
        mainly eye and mouth
        
        increases salivation and help in eye problems treatment
        
        if toxicity happen use atropin