Please enable JavaScript.
Coggle requires JavaScript to display documents.
Altered Hormonal Function, Glucocorticoids elevation - Coggle Diagram
Altered Hormonal Function
Excess production of TSH by thyroid gland
Binding of IgG antibodies to TSH receptors
Graves Disease
Suppression or activation of TSH depending on circulating thyroid hormone
Impaired negative feedback
Hyperthyroidism
Goiters, sweating, heat intolerance, weight loss, tremors
Serum TSH levels, elevated T3 and T4
Reduction of thyroid hormone levels
thyroid gland removal, pharmacologic intervention
Excess hormone secretion
Damage (inflammation, hypoxia) leads to problems w/ production and secretion of hormones
Hypothalamic-Pituitary Axis
Decreased Hormone secretion
Hypopituitarism
GnRH, GRHR, TSH,FSH, ACTH, ADH
Hyperpituitarism
Inappropriate ADH secretion
Decreased urine output, nausea/vomiting, headaches, irritability
hyponatremia (>135 mEq)
Decreased urine volume,
High concentration of sodium in urine
Removing SIADH
water restriction, IV solutions
Absent or weak hormone secretion
Endocrine Gland damage
Insufficient ADH production
Diabetes Insipidus
Polyuria, polydispia
ADH levels,Urine specific gravity (1.0005 or less)
Hydration, vasopressins
Caused by autoimmunity, iodine deficiency
Hormone deficiency
Impaired TSH/ TRH secretion
Thyroid Gland destruction
Hypothyroidism
Weakness, weight gain, dry skin,
T4 levels, thyroid antibodies, sensitive assay
Symptom management, pharmacologic intervention (levothyroxine)
Tumors in pituitary and adrenal gland
stimulation of ACTH and cortisol
Ectopic production
Cushing Syndome
Moon face, skin ulcers, hirsutism
urine collection (excess cortisol secretion)
Surgery, radiation
Deficient ACTH production
increase production of glucocorticoids, mineralocorticoids, androgens
Addison Disease
Hyperpigmentation, skin melanocytes
Lab levels of hyponatremia and hyperkalemia
IV fluid, antibiotic therapy, salt intake
Glucocorticoids elevation