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immunity - Coggle Diagram

- - - - lipids and nucleic acid
        
        will be antigenic
        
        proteins
        
        sugar
      - haptens
        
        molecules that will be recognized when attached to carrier
      - microbes
        
        capsule
        
        toxin
        
        cell wall
      - non microbes
        
        pollen
        
        egg white
        
        RBC
        
        molecules from transplanted tissue
  - - - helps in signal transduction
  - - - pentamer
      - trancytosis
      - first secreted once an antigen come
      - first secreted by the infant
      - half life is 2-3 days
      - binds the complement
      - protect against the blood borne pathogens
      - agglutinating antigen particles
    - - most common
      - 4 subclasses
      - monomer
      - viruses, bacteria and bacterial toxins
      - opsonisation
      - neutralize the activity of toxins
      - binds the complement
      - cross the placenta ( neonatal immunity)
      - half life 23 days
    - - dimmer in body secretions
      - it will provide a protective coat for the mucosal surfaces against the microbial colonization and adherance
      - transported by trancytosis by the polymeric immunoglobulin receptor pluR
      - transfer by breast milk
      - serum and body secretion (saliva, tears,GIT fluid, lungs )
      - half life 6 days
    - - bind to mast cells
        
        inflammation by histamine
        
        hypersenstivity
      - plays a role in parasitic helminthic infections
      - in allergy reactions
      - present in respiratory and intestinal epithelium
      - monomer and half life is 2 days
    - - monomer
      - immunoregulatory function
      - surface of B cells
  - - - IgG1
      - IgE
    - - IgA
    - - IgG2b
      - IgA
    - - IgG3
      - IgG2a