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GO (crosslinking, water uptake), strengthen polymer network, silica -…
GO
crosslinking
substantionally stable
water uptake
strengthen polymer network
covalent crosslinking (electron sharing)
ether bonds
noncovalent crosslinking
no sharing electron pairs
hydrogen bonds
π–π stacking (aromatic rings vs pi bond)
hydrophobic interactions
ionic crosslinking
chitosan amino group (positively charged) and negatively charged polyanion
two oppositely charged moieties
dipole-dipole intermolecular forces
Schiff-base linkage
self-healing
silica
Conjugation of drugs to macromolecular carriers is a proven strategy for improving pharmacokinetics