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Ch. 9 - The Luteal Phase - Coggle Diagram
Ch. 9 - The Luteal Phase
Three major processes
Synthesis and Secretion: growth and development of the corpus luteum accompanies by increasing quantities of progesterone
The primary target of progesterone is:
- Hypothalamus
- Uterus
- Mammary gland
Uterus has two target components:
- Glandular endometrium
- Muscular myometrium
The presence of basal (tonic) LH and cholesterol is necessary for progesterone to be secreted by luteal cells
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Luteolysis: destruction of the corpus luteum
- Accompanied by rapidly declining bood progesterone that results in a subsequent follicular phase
Regression of the CL is brought about by PGF2a that is synthesized and secreted by the uterine endometrium in most mammals and by the ovary in women
A vascular countercurrent transport system ensures that PGF2a will reach the ovary in sufficient quantities to cause luteolysis in the ewe, cow and sow
The negative feedback exerted by progesterone on the hypothalamus is removed and the female enters a new follicular phase because the pulse frequency and amplitude of GnRH increases thus allowing FSH and LH to increase
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Luteolysis results in:
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Removal of negative feedback by progesterone upon GnRH secretion resulting in a new follicular phase
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Leutenization: the transformation of theca interna and granulosa follicular cells into luteal cells after ovulation
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The luteal phase lasts from the time of ovulation until luteolysis of the corpus luteum (CL) near the end of the estrus cycle
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