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CAFFEINE INTAKE, SOD1 rs2070424 polymorphism: A alele reduces SOD1…
CAFFEINE INTAKE
ADORA2A GENE POLYMORPHISM rs5751876
CC
CT
TT
ANXIETY
increase in SOD activity
decrease in oxidative stress
increased SOD activity
increased PKA levels
c-Raf-1 is inactivated
NF-kb is not induced
Alzheimer's disease related proteins are not produced
increase in dopamine concentration
mood improvement
ADORA2A GENE POLYMORPHISM rs35320474
CT and TT
ANXIETY
ADORA2A GENE POLYMORPHISM rs5751876
CC
sleep impairments
CYP1A2 polymorphism rs762551
AC and CC
slow caffeine metabolism
reduced sleep quality in case of afternoon intake
lipid peroxidation inhibition
improved mitochondrial functioning
anti-inflammatory
increase in BDNF
increased energy metabolism in brain
SOD1 rs2070424 polymorphism: A alele reduces SOD1 activity
COGNITION
BRAIN
MOOD
MOOD
SLEEP
BRAIN
SLEEP
MORE BENEFITS FROM CAFFEINE