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Coevolution - Coggle Diagram
Coevolution
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Adaptive
Type of antigens:
CD1d cells:non-polymophic, MHC classI-like molecules that presents phospholipid and glycosphingolipid Ags.
MR1 T cells : non-polymorphic MHC class I-like that presents a family of bacteria derived metabolites to MAIT cells
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γδ T cells: human gamma delta T cells can exhibit an antigen-presenting capacity. express a unique T- cell receptor composed of one gamma and one delta chain
Recognize phosphorylated antigens that accumulate in cancer cells and also can recognize MHC class I chain related molecles
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MHC class I: class I and II proteins share the task if presenting peptides on the cell surface fro recognition by T cells
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Innate
NTK cells: a group of heterogeneous T cells that recognize glycolipid antigens present by MHC class I protein CD1d. Also known as the first line of defense.
Activing signals : Activition of immune responses due to the presence of pathogens evolves the release of cytokine
FGF: Activated FGF signaling plays a role in suiting stem cells capbaiblites through activation of RAS, MAPK, etc
Inhibitory signals/receptors : Natural killer cells inhibitory receptor Ly49Iare, described as ectracelluar ligand interacting regions
Inhibitory receptors on Lymphocytes: critical regulators of adaptive immune responses to infections while limiting autoimmunity
KIR(Killer Ig-like Receptors ): are surface inhibitory receptors specific for allelic forms of HLA class I molecules that are expressed by NTK cells and T lymphocytes.
CLR (lectin type receptor)important patter recognition receptor involved in recognition and induction of adaptive immunity to pathogens
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ADCC: makes use of the innate immune cells provides antitumor cytotoxicity activated by antibodies linked to target cells
CD16: a cluster of differentiation ,oelcule found on the surface go natural killer cells