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Cushing Syndrome, Muhammad Zubair, 2108260216 - Coggle Diagram
Cushing Syndrome
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Tatalaksana
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Pituitary, adrenal direct agent drugs
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CMD
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Clinical/Lab examination: Dexametasone suppresion test, Cortisol test, CT scan, MRI
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Definisi dan Ciri
Cushing's syndrome is a collective of symptoms that appears as a result of high levels of Cortisol hormone in the body.
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Prognosis & Education
Prognosis for Cushing's disease is generally good if Diagnosis and therapy is carried out quickly and precisely.
Regular exercise, Quit smoking, Consume nutritious food, Lose weight, Stop alcohol, Control blood sugar levels.
Etiology
1.Adenoma Pituitary
- Hyperplasia Corticotroph
3.Corticosteroid Drugs
Patophysiology
Peak release of ACTH occurs just before awakening, and ACTH levels then decrease throughout the day. This diurnal pattern of release is independent of the amount of circulating cortisol. Cushing's disease adenomas secrete an excessive amount of ACTH, but they typically still exhibit some negative feedback responsiveness to high doses of glucocorticoids. Ectopic sources of ACTH, which typically take the form of extracranial neoplasms, do not typically react negatively to strong glucocorticoid doses.
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