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The Follicular Phase - Coggle Diagram
The Follicular Phase
Ovulation
preovulatory surge of LH
hyperemia to the dominant follicle
dominant follicle begins secreting progesterone
collagenase breaks down collagen in the ovary and allows follicle to grow even larger
release of prostaglandins to increase blood flow and increase contraction of ovarian smooth muscle
induced ovulators
sensory nerves in the vagina send signals to the surge center in the brain to induce ovulation
Increase GnRH from the hypothalamus
Progesterone negative feedback loop is removed
High estrogen and low progesterone triggers the surge release of GnRH from the hypothalamus
Required to begin the follicular phase
Driven by luteolysis
CL is no longer functioning
Decreased levels of progesterone
Negative feedback loop on the hypothalamus is removed & GnRH can be released
Increase GnRH leads to increased release of LH and FSH
Control follicular dynamics (growth and death of follicles)
Recruitment
group of follicles emerge
start secreting estrogen
Selection
group of growing follicles that have not undergond atresia
some may become dominant
secrete estradiol and inhibin
Dominance
1 follicle in cows, horse, and woman
many follicles in dogs, cats, pigs
Dominant follicle(s) emerges and produces inhibin and estradiol
The dominant follicle must have enough LH receptors in order to be able to respond to high levels of LH to become dominant
Atresia
degeneration
most recruited follicles end up becoming atretic
Inducing changes for receptivity
increased circulating estradiol
increased blood flow
genital swelling
leukocytosis
increased mucus production
elevated myometrial tone
Female stands to be mounted by the male
