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Hashimoto's Thyroiditis - Coggle Diagram
Hashimoto's Thyroiditis
Thyroid Physiology
Produces thyroid hormones: calcitonin, triiodothyronine, and thyroxine
Involves thyrocytes (follicle cells), capillary, and the colloid
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Education and Prognosis
Prognosis
Patients with Hashimoto's Thyroiditis would have a good prognosis if treated quickly and properly. If not treated quickly and properly, Hashimoto's will cause complications and can lead to morbidity up to 60%.
Education
Rest well, eat high nutrition foods, healthy lifestyle, consume sodium levothyroxine.
Risk factors
Sex, age, radiation exposure, genetics, pregnancy, excessive or deficiency iodine intake
Patophysiology
too much TSH. Another term for Hashimoto disease is autoimmune thyroiditis. Goiter formation is significant in this form of hypothyroidism due to inflammation. Inflammation is caused by stimulation of CD4 and T helper cells that are explicit to your thyroid. This stimulation can be either viral or bacterial in presence. The influx of CD4 and T helper cells as well as activation of other autoantibodies produced by the B helper cells causes destruction of thyroid tissue. Apoptosis is activated by CD8 cells and is significant in the destruction as well.
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Etiology of Hashimoto's
The etiology of this Thyroiditis is still poorly understood, but autoimmunity as result from the self-tolerance breakdown is often associated.
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Environmental factors (bacteria, viruses, drugs, decreased iodine intakes).
Differential Diagnosis
Grave disease, sub acute thyroiditis, post partum thyroiditis, thyroid cancer, riedel thyroiditis.
Diagnosis Mechanism
History taking
Swelling of something in neck, myopathy, puffy face, hair loss, hypothyroid inheritance from her mother, diagnosed hypothyroid 3 months ago
Physical examination
Vital sign all normal, mass felt around on the neck.
Supportive examination
TSH levels increased, T4 levels and T3 levels normal, Anti-TPO levels increased
Clinical Manifestation
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Muscle aches, tenderness and stiffness
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Thyroid Anatomy
Consists of 3 lobes: Pyramid lobe, right lobe, and left lobe and connected by isthmus
the thyroid gland lies posterior to the sternothyroid and sternohyoid muscles, wrapping around the cricoid cartilage and tracheal rings. It is located inferior to the laryngeal thyroid cartilage, typically corresponding to the vertebral levels C5-T1.