Uterine/Cervical Cancer

Physical Findings

DIAGNOSTIC TESTS

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Maternal serum testing of chromosomes

PRENATAL TESTS
1) Karyotype Analysis
2) Amniocentesis
3) Chorionic villous sampling
4) Ultrasound

Symptoms after birth

1) Short stature (scoliosis)
2) Broad chest
3) Droopy eyelids
4) Short and wide neck
5) Small and lower jaw
6) Nail fragility and lack of growth

Physical Findings

Atypical Sexual Development
1) Delay in puberty
2) Limited or no sex hormones
3) Lack of breast development
4) Smal ovaries
5) Lack of menstrual cycle

TREATMENTS

CAUSATIVE FACTORS

Estrogen/progestogen contraceptives
Approximately 30% Turner Syndrome cases
Some cells have two X Chromosomes and some cells have only one.
Random error in cell division.

Diethylstilbestrol
Some X chromosome material was transferred to the child.
Rare case.

Behavioral/Psychological Therapy

Occupational therapy

Hormone Therapy

Growth hormones

Oxandrolone therapy (r-hGH or combination with androgen)

Estrogen therapy

Tobacco smoking

HIV Type 1

Human Papillomavirus
Approximately 45% TS cases
Each cell contains one X chromosome instead of two X chromosomes.

PATHOPHYSIOLOGICAL ETIOLOGY