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Pediatric Cancer, Acute Tumor Lysis Syndrome, Leukemia , Rhabdomyosarcoma,…

- - - - Alopecia (hair loss)
      - GI probelms
        
        Nutrition (small means, give choice)
        
        Constipation/diarrhea
        
        Nausea/vomiting (48 hrs)
        
        Mucosal ulceration
      - Extravasation (leakage of blood, lymph, or other fluid from a blood vessel or tube into the tissue around it)
      - GU probelms: hemorrhagic cystitis
      - Neuropathy
      - Myelosuppression
        
        Nadir: lowest blood count
        
        Anemia
        
        Epoetin alfa
        
        Transfusion if HgB <7
        
        Usually within 7-10 days after drug given
        
        Neutropenic fever
        
        EMERGENCY: GOLDEN HOUR: put on EML/LMX, go to ED, access port, draw labs and cultures, start antibiotics
- - - - Destroys cells
- - - - Pancytopenia
        
        Thrombocytopenia
        
        Neutropenia
        
        Anemia
      - Blast present
- - - - Enlarged, movable nodes
      - Supraclavicular or cervical area
  - - - reed sternberg cells
        
        large, abnormal lymphocytes (a type of white blood cell) that may contain more than one nucleus
- - - - Lymphoblastic
      - Burkitt
      - Non-Burkitt
      - Large cell