Please enable JavaScript.

Coggle requires JavaScript to display documents.

MACROPHAGES, PRR, INDUCED INNATE RESPONSE - Coggle Diagram

- - - - ILCs
        
        NK cells
        
        produces
        
        IFN-γ
        
        target
      - neutrophils
    - - IL-6
        
        Acute-phase proteins
        
        CRP
        
        triggers
        
        Classic Pathway
        
        activates
        
        1 more item...
        
        MBL
        
        initiates
        
        Lectin Pathway
        
        activates
        
        1 more item...
        
        Complement
        
        generates
        
        C3b
        
        associated with
        
        1 more item...
        
        opsonizes
        
        bacteria
        
        activating
        
        phagocytosis
        
        2 more items...
      - IL-12
        
        positive feedback
      - TNF-α
      - CXCL8
- - - - IL-1β
        
        in infected tissue activates more
- - - - signaling
- - - - TBK1
        
        IRF7
        
        initiates transcription
        
        IFN-α
        
        IRF3
        
        initiates transcription
        
        IFN-β
        
        activate