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Connective Tissues , Resident Cells, Protein fibres, Transient cells, ECM…

- - - - Fibroblasts
      - mast cells
      - Adipose cells
      - fixed macrophages
  - - - Leukocytes
      - Macrophages
      - Neutrophils
      - Lymphocytes
- - - - antigen presentation for immune response
      - antigen presentation
      - release cytokines
      - produces fibres
    - - heal damaged tissues
- - - - For treatment, the adipocytes are targeted to not activate the adipocytes
- - - - triple helix assembly
        
        fibrils assemble and with covalent cross linking
- - - - genetic disease caused by Col1A1 gene mutation causing defect in collagen synthesis
      - bones are very fragile
- - - - antihistamines for treating cancer as well
- - - - present in cancer and can be detected for treatment
- - - - lamina propria of tunica mucosa
      - tunica intima of blood vessels
      - stroma in solid organs
  - - - regular - tendons, ligaments
        
        parallel collagen bundles for squeezing
      - regular bundles - cornea
        
        orthogonal collagen fibres
      - irregular - dermis
        
        collagen fibres irregularly dispersed for tensile strength
  - - - White fat and depends on nutritional status
      - Stores energy substances, thermal insulation, organ protection and hormone production
      - nucleus at periphery, no rER, small Golgi, some mitochondria, BIG lipid
      - many blood capillaries
      - produces leptin hormone for control of appetite and satiety
    - - Stores energy in the form of triglycerides
      - Regulate energy and metabolism by secreting factors
      - Cushion organs
    - - mainly in children
      - lipid degradation for HEAT
      - many lipid droplets, mitochondria and blood vessels