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histo 2: non membranous organelles - Coggle Diagram
histo 2: non membranous organelles
Ribosomes
MF: protein synthesis
basophilic due to attached rRNA
electron dense granule 20-30um
consist of 2 subunits = large+small
formed of protein & rRNA
types: free & attached
free: used in the cell
attached: used outside the cell
microfilaments
thread like structure
3 types
thin: actin + 6-7um + contractile
microvilli for their movement
cleavage furrow
muscle contraction
thick: myosin+ 12-16 um+ contractile+ myofibril
intermediate: 5 types+ 10-12um+ noncontractile(desmin, neurofilaments, cytokeratin)
determine the shape of the cell
cell type specific marker
identification of tumor
microtubules
pipe like structure
fixed diameter =25nm - unfixed length
contain tubulin protein
functions
main structure of cilia, flagella and centriole
act as guiding tracks for the organelles
mitotic spindle formation
cytoskeletal structure
Centriole
H&E stain: not seen ----> iron H: 2 dark blue granules found in the juxtanuclear position
consist of 27 microtubules arranged in 9 bundles, each bundle contain triplets of microtubules
functions:
plays and impo role in cell division
undivided cells, act as center which all organelles are polarized
in ciliated cells, act as basal bodies for the cilia
Cilia
hair less processes 10-15um
found in the respiratory system & female gentile system
seen vaguely in the cavity --- several hundred cells
shaft: consist of 20 microtubules arranged in 9 peripheral doublets & 2 single central microtubules
basal body --- formed of centriole
beating in one direction
flagella
found in the sperm tail
whip like swimming movement
one flagella in one cell
longer than cilia---> 200um
cell inclusion
stored food
CHO---> glycogen granules
lipids ---> small droplets & large globules
pigments
exogenous
lipochrome pigment---> carotene
minerals
dust---> black pigments
tattoo marks
endogenous
derivatives of hemoglobin ---> bilirubin
melanin
hemoglobin
lipofuscin ---> golden brown
crystals