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Systemic Lupus Erythematosus (SLE), Causes of Systemic lupus Erythmatosus,…
Systemic Lupus Erythematosus (SLE)
Autoimmune disease
chronic inflammatory disease
Impaired skin integrity
Inflammation
Acute Pain
Fatigue
anemia
Depression
Impaired motility
Joints issues/ arthritis
Neurologic issues
seizures
psychosis
strokes
Complications
Kidneys. Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus.
Brain and central nervous system. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, vision problems, and even strokes or seizures. Many people with lupus experience memory problems and may have difficulty expressing their thoughts.
Blood and blood vessels. Lupus may lead to blood problems, including a reduced number of healthy red blood cells (anemia) and an increased risk of bleeding or blood clotting. It can also cause inflammation of the blood vessels.
Lungs. Having lupus increases your chances of developing an inflammation of the chest cavity lining, which can make breathing painful. Bleeding into the lungs and pneumonia also are possible.
Heart. Lupus can cause inflammation of your heart muscle, your arteries, or your heart membrane. The risk of cardiovascular disease and heart attacks increases greatly as well.
Testing
Complete blood count. This test measures the number of red blood cells, white blood cells, and platelets and the amount of hemoglobin. Results may indicate you have anemia, which commonly occurs in lupus.
Erythrocyte sedimentation rate. This blood test determines the rate at which red blood cells settle to the bottom of a tube in an hour. A fast rate may indicate a systemic disease, such as lupus.
Kidney and liver assessment. Blood tests can assess how well your kidneys and liver are functioning. Lupus can affect these organs.
Urinalysis. An examination of a sample of your urine may show an increased protein level or red blood cells in the urine, which may occur if lupus has affected your kidneys.
Antinuclear antibody (ANA) test. A positive test for the presence of these antibodies indicates a stimulated immune system.
Imaging tests examples
Joint radiography
Echocardiography
Brain MRI/MRA
Treatments
Nonsteroidal anti-inflammatory drugs (NSAIDs)
Antimalarial drugs. Medications commonly used to treat malaria, such as hydroxychloroquine (Plaquenil), affect the immune system and can help decrease the risk of lupus flares.
Corticosteroids. Prednisone and other types of corticosteroids can counter the inflammation of lupus.
Immunosuppressants
Biologic drugs. There are substance that is made from a living organism or its products and is used in the prevention, diagnosis, or treatment of cancer and other diseases.
Genetic factors
environmental factors
hormonal factors
Being a women age 15-45
Asian, African Americans and Hispanics background
Genetics/ family history
Causes of Systemic lupus Erythmatosus
Risk factors