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DEPRESI - Coggle Diagram
DEPRESI
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EDUCATION
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Exercise regularly, at least 3-5 times a week with a duration of about 30 minutes.
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KOMPLICATION
Being overweight or obese, which can lead to heart disease and diabetes.
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PATHOPHISYOLOGY
Clinical and preclinical trials suggest a disturbance in central nervous system serotonin (5-HT) activity as an important factor. Other neurotransmitters implicated include norepinephrine (NE), dopamine (DA), glutamate, and brain-derived neurotrophic factor (BDNF).
DIAGNOSIS
These are the 9 symptoms listed in the DSM-5. Five must be present to make the diagnosis (one of the symptoms should be depressed mood or loss of interest or pleasure):
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PROGNOSIS
Major depression has very high morbidity and mortality contributing to high rates of suicide. Even though effective drug treatment is available, nearly 50% may not initially respond. Complete remission is not common but at least 40% achieve partial remission in 12 months.