Connective Tissue
adult tissue
irregularly arranged CT
dense irregular
muscle attachments, fascia lata, and tendons
areolar (loose irregular)
CT cells
fiber and ground substance producers
fibroblasts
chondroblasts
osteoblasts
odontoblast
immunologic
plasma cell
eosinophil
macrophage
neutrophil
mast cell
basophil
special
regularly arranged dense CT
adipose
reticular
CT fibers
collagen
elastic
type I
type II
type III
type IV
matrix
supportive
cartiledge
bone
joints
may be residents or wanderers
create extracellular fibers and ground substance
can remain quiescent
can de-differentiate to become other cell types
resident cell
common in loose CT (skin, intestine, around blood vessels)
rich in histamine and heparin
resident or immigrant
derive from blood monocytes
vacuolated
phagocytic, go where there is a mess
immigrant
derived from B-lymphos in blood
often located in intestinal mucosa, uterus, lymphoid organs, sites of inflammation
wagon wheel appearance
produce antibodies
most common in body
locations
dermis
fascia
bones
ligaments
tendons
organized into regular or irregular bundles
high tensile strength
reticular fibers
coated by proteoglycans and glycoproteins
needs silver stain
locations
beneath basal lamina
surrounds muscles
capillaries
nerves
adipose tissue
supports and binds cells
integral part of basement membrane
locations
vocal cords
epiglottis
lungs
aorta
dermis
contains elastin
stretch up to 1.5-2.5x and return to original length
usually requires special stain
ground substance
contain proteoglycans and glycoproteins
can retain a large amount of tissue fluid
makes up basement membrane, which is beneath all epithelia
does not organize into fibrils
colorless semi-fluid filling spaces between cells and fibers
basal laminae
type IV collagen
reticular lamina (type III collagen)
unilocular
multilocular (brown fat)
hibernating animals
neonates
multiple lipid droplets
multiple mitochondria for heat generation
central nucleus
peripheral nucleus
mostly composed of one large lipid droplet
most common adipose
tendons
ligaments