Please enable JavaScript.

Coggle requires JavaScript to display documents.

Hormones - Coggle Diagram

- - - - Gs increase
      - Gi lower
        
        ATP to cAMP
        
        active Protein Kinase A
        
        add phosphate
        
        CREB
        
        increase gene expression
        
        stimulate phosphorilation
        
        enzymes
  - - - alpha
        
        active GTP
        
        inactive GDP
      - beta
      - gamma
    - - increase cAMP
    - - lower cAMP
    - - increase Ca+
  - - - turns PIP2 to IP3
        
        open calcium chanell in ER
        
        increase Ca+ in cell
        
        DAG
        
        stimulate PKC
        
        Gene expression
        
        phosphorylate enzymes
  - - - GTP to cGMP
        
        active Protein Kinase G
        
        relaxation of smooth muscle
    - - Nitric oxide
        
        NO activate soluble guanylate cyclate
  - - - autophosphorylation
        
        uses 2 atp to make 2 ADP
        
        IRS bind to phosphorylated receptor
        
        SH2 bind to phosphate
        
        protein phosphatase
        
        active p21ras G protein
        
        gene expression
        
        translocation of GLUT-4
        in adiposite and muscle
- - - - membrane
    - - Protein Kinase
    - - in minutes
    - - cAMP binding CREB
        in hours
    - - Glucagon
      - Catecholamines
      - Insulin
  - - - inside
    - - to enhancer regions
    - - in hours
    - - steroids
      - calcitriol
      - thyrotoxines
      - retinoic acid