Please enable JavaScript.
Coggle requires JavaScript to display documents.
Antibiotic resistance associated mutations - Coggle Diagram
Antibiotic resistance associated mutations
What are the objectives
Sensitivity, specificity and comparison of different diagnostic tests
Confirm isolates from Hospital-Acquired Bacterial Infections by gene sequencing
Evaluate drug susceptibility
Amplification of antibiotics resistance genes
Detect genes mutations
Microbes living in different environmental conditions have genetic diversity
What are the steps
DNA extraction, PCR, Gel electrophoresis, sequencing
Drug susceptibility testing (DST)
identification and Culturing
Antibiotics resistance genes amplification and sequencing
Samples collections and screening
Mutational analysis and genetic diversity
Novality
Bacterial strains vary from region to region. Genetic diversity contributes to the variability in disease presentation, frequency of transmission, and treatment outcome
s
Designing novel drugs to overcome resistance problems
How long does it take to conduct
DNA extraction, PCR, Gel electrophoresis and sequencing 06 Months
DST 02 Months
Identification and culturing 02 months
Mutational analysis of genes and genetic diversity 06 months
Samples collection and screening 02 months