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Neurofibromatosis 2, references: - Coggle Diagram
Neurofibromatosis 2
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management
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meningioma: surgical, radiation therapy, lapatinib, bevacizumab
intramedullary spinal tumors: grade I-II ependimomas, surveillance, surgery rarely indicated
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clinical features
neurologic
intracreanial meningiomas: 75%, multiple
spinal tumors: schwannoma, meningioma, ependymoma
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bilateral vestibular schwannomas - 30y 95%: tinnitus, hearing loss, brainstem compression, hydrocephalus
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prognosis
wheelchair early adulthood: poor balance, weakness, visual problems
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references:
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Author:D Gareth Evans, MD, FRCPSection Editors:Jay S Loeffler, MDPatrick Y Wen, MDDeputy Editor:April F Eichler, MD, MPH
UpToDate. Literature review current through: Jun 2020. | This topic last updated: Feb 14, 2020.