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CVS Pathology 1 - Coggle Diagram

- - - - Vegetative
        
        Endothelial damage
        
        Fibrin deposition
        
        Rough nodular lesions
        
        Localised thrombosis
        
        Embedded bacterial colonies + leukocytes
        
        Septic emboli lodged
        
        Abscessation + infarction
        
        Snake envenomation
      - Left AV valve most susceptible :!:
    - - Bacterial septicaemia
      - Uraemic ulcerative endocarditis
        
        Renal failure -dogs
  - - - Smooth nodular lesions
      - Collagen degeneration
        
        Fibroblastic proliferaion
        
        Acid mucopolysaccharide deposits
    - - Left CHF
      - Cavalier predisposition
- - - - Generalised oedema
        
        Ascites, hydrothorax
        
        Hypoproteinaemia
        
        CHF - dilated cardiomyopathy
      - Outcome
        
        Cardiac tamponade
        
        Prevents cardiac filling + venous return
    - - Causes
        
        Atrial rupture (dogs)
        
        Intrapericardial aorta rupture (Horses)
        
        Cardiac injection complications
  - - - Traumatic reticulo-peritonitis (TRP)
        
        Reticulum penetration
        
        Acute local peritonitis
        
        Diaphragm penetrated
        
        Pleuritis ; pneumonia
        
        Septicaemia - endocarditis
        
        Fluid accumulation - pericardial sac
        
        Cardiac tamponade
        
        :arrow_down: SV + CO
        
        Compensatory myocardial hypertrophy
        
        Acute congestive HF
        
        Chronic inflammatory lesion
        
        Fibrous adhesions
        
        Visceral to parietal pericardium
        
        Heart constriction
        
        Abscessation
    - - Haematogenous spread
        
        Strep (horses)
        
        Cattle - pasteurellosis, black leg, coliform septicaemias
      - Adhesions, exudate
- - - - :arrow_up: contractile force + SV
        
        :arrow_up: Cardiac output
        
        :arrow_up: chamber size
      - Overexertion
        
        :arrow_down: contractile strength
        
        Congestive heart failure
    - - :arrow_up: Myocyte mass and size
        
        Non-regenerative - permanent cells
      - Increased workload
        
        Pressure / volume overload
      - :arrow_down: ventricular chamber size
  - - - Toxoplasmosis
      - Black leg - cattle
    - - Parasitic myocarditis