Please enable JavaScript.
Coggle requires JavaScript to display documents.
p1 Benefits - Coggle Diagram
p1 Benefits
aim and steps
-
-
Genotyping can be performed using single-nucleotide polymorphism (SNP) arrays combined with imputation or whole- genome sequencing (WGS).
Causal variants are usually not directly genotyped but are in linkage disequilibrium with the genotyped SNPs.
Association tests are used to identify regions of the genome associated with the phenotype of interest at genome-wide significance
-
-
-
Genome- wide association studies (GWAS) involve testing genetic variants across
the genomes of many individuals to identify genotype–phenotype associations.
-
GWAS have revolutionized the field of complex disease genetics over the past decade, providing numerous compelling associations for human complex traits and diseases.
-
-
-
-
-
-