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BURN AFFECT DIGESTIVE SYSTEM - Coggle Diagram
BURN AFFECT DIGESTIVE SYSTEM
SEPSIS
A)Due to severe burn, loss of skin and damage to the blood vessels.
B)extravasation of plasma (Leakage of a fluid/blood loss)
C)Hypovolemic shock
D)Difficult for heart to pump a sufficient amount of blood to your body.
E)resulting in the ischemia and hypoxia of tissues.
F)ischemia/hypoxia caused pathogenesis of intestinal barrier dysfunction
G)disruption of intestinal barrier( mechanical, immunological, biological, and chemical barriers)
H)increased intestinal permeability and subsequent translocation of bacteria and/or endotoxin from the gastrointestinal tract
I)cause systemic inflammatory response syndrome, sepsis, multiple organ dysfunction syndrome
CURLING'S ULCER
A)reduced plasma volume leads to ischemia and cell necrosis (sloughing) of the gastric mucosa.
B) less blood will be available to supply the digestive system with oxygen and other nutrients.
C) Because the digestive organ do not receive enough oxygen and nutrients from the blood, cells in the organ begin to die off, which can result in the formation of an ulcer.
D) damage to the mucosal barrier secondary to systemic stress resulting in multiple superficial erosions of the gastric mucosa leads to ulceration
E) mucosal glycoprotein is denuded by increased concentrations of refluxed bile salts or uremic toxins due to a critical illness.
F) Result: Curling’s ulcer
Due to severe burn:
GASTRITIS
A)Due to: stressful physiologic event- severe burn to the skin
B)Stress- related hormone cause an alteration of pH can disrupt homeostatic digestion
C)resulting in dysregulation of gastric pH
D)Stress-induced gastritis/ inflammation of the stomach
E)Elevate levels of acetylcholine (muscarinic) and histamine
F)Result in increased acid production thus inducing gastritis
G)Symptoms- nausea or vomiting, burping, churning