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Hormonal and Metabolic Dysfunction - Coggle Diagram
Hormonal and Metabolic Dysfunction
SIADH secretion
Excessive Production and Release of ADH
Ectopic secretion of ADH
Decreased and concentrated urine output
Water restriction, hypertonic IV solution
Diabetes Insipidus
Insufficient production of ADH by hypothalamus
Polyuria and excessive thirst
Hydration, hypotonic IV solution
Ineffective secretion by posterior pituitary
Inadequate kidney response to ADH
Hyperthyroidism
Excessive thyroid hormone secretion
Weight loss, agitation, sweating, tachycardia, exophthalmos
Gland destruction
Excessive production of TSH by pituitary adenoma
Excessive metabolic rate
Hypothyroidism
Deficient thyroid hormone synthesis
Weight gain, lethargy, cold intolerance, myxedema
Thyroid hormone replacement therapy
Destruction of thyroid gland
Impaired TSH or TRH secretion
Cushing Syndrome
Excess secretion of glucocorticoids
Tumors that stimulate excess ACTH, cortisol, or CRH production
Obesity in trunk, face and upper back, osteoporosis, muscle weakness, hirsutism
Removing cause (surgery/radiation for tumors)
Addison Disease
Lack of ACTH production from pituitary
hypotension, weakness, poor stress response
Isotonic IV fluids, oral replacement of glucocorticoids and mineralocorticoids hormones
Lack of CRH
Lack of secretion of hormones from adrenal cortex