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ICU, Effects of reduced Tissue Perfusion, Cardiac Dysfunction, Cardiac…

- - - - causing the body to injure its own tissues instead of fighting the infection
        
        Tissues metabolic requirements are higher than the body can deliver = Inadequate tissue perfusion
  - - - Caused by systemic vasodilation that occurs to help get blood to infection site in hopes of fighting it
        
        Leads to slowing of entire circulatory system
        
        Which in turn leads to blood vessel leakage into interstitial spaces, and the blood never reaches the organs leading to organ failure. This also causes reduced capillary refill time.
        
        HR increases to account for lost pressure and inability to oxygenate organs and extremities
    - - Due to lost kidney function as it is one of the initial organs to shut down in effort to preserve more vital organs
    - - Caused by hypoxia in peripheral tissues. Body resorts to anaerobic metabolism for functioning with lactate as byproduct
- - - - Alveoli have serous exudates, pathogens, few neutrophils, and macrophages
        
        Consolidations formed
        
        Increased consolidations are correlated with increase bacteria which then lead to perfusion of bacteria into capillaries and into the bloodstream
        
        Lobe becomes consolidated & firm, alveolar walls are thickened
      - Cytokines are responsible for the leakage of the alveolar-capillary membrane at the site of inflammation
- - - - asymptomatic
      - fever, chills, shaking or shivering
      - pain, nauseau, diarrhea