On September 15, 1521, King Carlos V, by means of a Royal Certificate issued in Burgos, granted the population of Panama the title of City and a coat of arms. Later, by means of a Royal Certificate issued in Lisbon on December 3, 1581, Felipe II granted him the title of "Very Noble and Loyal City", in gratitude for the services rendered against rebels to the Crown. At the end of 1519, Captain Diego was ordered of Albitres who would once again populate Nombre de Dios, founded by Diego De Nicuesa, in order to have a population that would serve as a base in the north of the Isthmus, since Acla did not provide adequate facilities. By means of a Royal Certificate of 1537, the Emperor Carlos V granted the name of God the name of "city", and on December 7 of that same year, he gave him a coat of arms with the motto "In nómine meo foveat me" (Help me in my Name). Between both cities, each located in the Atlantic and the Pacific, a "Camino Real" was established to transport the various species that passed through the Isthmus.